GOPC 抗体 (AA 164-193)
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北京 101111
Quick Overview for GOPC 抗体 (AA 164-193) (ABIN391395)
抗原
See all GOPC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 164-193
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预测反应
- M
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the Central region of human PIST.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
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别名
- PIST
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背景
- PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
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分子量
- 50520
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基因ID
- 57120
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NCBI登录号
- NP_001017408, NP_065132
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UniProt
- Q9HD26
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途径
- Maintenance of Protein Location, Asymmetric Protein Localization
抗原
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