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DCLK1 抗体 (N-Term)

This anti-DCLK1 antibody is a 兔 多克隆 antibody detecting DCLK1 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN391323
发货至: 中国

Quick Overview for DCLK1 抗体 (N-Term) (ABIN391323)

抗原

See all DCLK1 抗体
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

适用

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人, 小鼠

宿主

  • 81
  • 16
  • 1

克隆类型

  • 65
  • 33
多克隆

标记

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This DCLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB3059
  • 抗原表位

    • 15
    • 9
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    AA 1-30, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This DCAMKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCAMKL1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Sala, Matthews, Speer, Torashima, Barthel, Grikscheit: "A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse." in: Tissue engineering. Part A, Vol. 17, Issue 13-14, pp. 1841-50, (2011) (PubMed).

    Tu, Quante, Bhagat, Takaishi, Cui, Yang, Muthuplani, Shibata, Fox, Pritchard, Wang: "IFN-? inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T-cell apoptosis." in: Cancer research, Vol. 71, Issue 12, pp. 4247-59, (2011) (PubMed).

    Shibata, Takaishi, Muthupalani, Pritchard, Whary, Rogers, Fox, Betz, Kaestner, Karin, Wang: "Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia." in: Gastroenterology, Vol. 138, Issue 3, pp. 1022-34.e1-10, (2010) (PubMed).

    Jin, Ramanathan, Quante, Baik, Yang, Wang, Tu, Gordon, Pritchard, Varro, Shulkes, Wang: "Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice." in: The Journal of clinical investigation, Vol. 119, Issue 9, pp. 2691-701, (2009) (PubMed).

    Gyamfi, Tanaka, He, Klaassen, Wan: "Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice." in: Toxicology and applied pharmacology, Vol. 234, Issue 2, pp. 166-78, (2009) (PubMed).

  • 抗原

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    别名

    DCAMKL1

    背景

    Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.

    分子量

    82224

    基因ID

    9201

    NCBI登录号

    NP_001182344, NP_001182345, NP_004725

    UniProt

    O15075
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