PIM3 抗体 (C-Term)
(5 references)Quick Overview for PIM3 抗体 (C-Term) (ABIN2841313)
抗原
See all PIM3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 259-288, C-Term
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human PIM3.
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亚型
- Ig Fraction
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anti-Pim-3 Oncogene (PIM3) (AA 278-326) antibody
PIM3 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pim-3 Oncogene (PIM3) (AA 259-288), (C-Term) antibodyPIM3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB8591 unconjugated
anti-Pim-3 Oncogene (PIM3) (AA 259-288) antibodyPIM3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pim-3 Oncogene (PIM3) (AA 242-326) antibodyPIM3 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4A9 unconjugated
anti-Pim-3 Oncogene (PIM3) antibodyPIM3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pim-3 Oncogene (PIM3) (AA 247-326) antibodyPIM3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pim-3 Oncogene (PIM3) (AA 1-326) antibodyPIM3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Expression and significance of Pim-3 kinase in adult T-cell leukemia." in: European journal of haematology, Vol. 99, Issue 6, pp. 495-504, (2018) (PubMed).
: "PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1)." in: Molecular cancer therapeutics, Vol. 13, Issue 5, pp. 1231-45, (2014) (PubMed).
: "PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma." in: British journal of cancer, Vol. 107, Issue 3, pp. 491-500, (2012) (PubMed).
: "Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells." in: Blood, Vol. 114, Issue 19, pp. 4150-7, (2009) (PubMed).
: "KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA." in: PLoS pathogens, Vol. 5, Issue 3, pp. e1000324, (2009) (PubMed).
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: "Expression and significance of Pim-3 kinase in adult T-cell leukemia." in: European journal of haematology, Vol. 99, Issue 6, pp. 495-504, (2018) (PubMed).
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- PIM3 (Pim-3 Oncogene (PIM3))
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别名
- PIM3
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背景
- PIM3 is a memberof the Ser/Thr protein kinase family that may be involved in cell cycle progression and anti-apoptosis process. This protein has been implicated in proliferation of human hepatoma cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine. PIM3 is expressed in human hepatoma cell lines but not in normal liver tissues.
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分子量
- 35891
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基因ID
- 415116
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NCBI登录号
- NP_001001852
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UniProt
- Q86V86
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途径
- Negative Regulation of Hormone Secretion
抗原
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