PDXK 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PDXK 抗体 (C-Term) (ABIN391248)
抗原
See all PDXK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 242-272, C-Term
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-272 amino acids from the C-terminal region of human PDXK.
-
亚型
- Ig Fraction
-
-
anti-Pyridoxal Kinase (PDXK) (AA 29-253) antibody
PDXK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 29-285) antibodyPDXK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 35-251) antibodyPDXK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5H5 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 51-160) antibodyPDXK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyKD Validated PDXK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB5170 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000. IHC-P: 1:50~100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- PDXK (Pyridoxal Kinase (PDXK))
-
别名
- PDXK
-
背景
- Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.
-
分子量
- 35102
-
基因ID
- 8566
-
NCBI登录号
- NP_003672
-
UniProt
- O00764
抗原
-
