PANK2 抗体 (AA 180-210)
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北京 101111
Quick Overview for PANK2 抗体 (AA 180-210) (ABIN391238)
抗原
See all PANK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 180-210
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human PANK2.
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亚型
- Ig Fraction
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anti-Pantothenate Kinase 2 (PANK2) antibody
PANK2 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H9 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 437-490) antibodyPANK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 205-260) antibodyPANK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 300-400) antibodyPANK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (N-Term) antibodyPANK2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 459-508) antibodyPANK2 适用: 人, 大鼠, 犬, Cow, 马, 绵羊, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) antibodyPANK2 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 3G4 unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PANK2 (Pantothenate Kinase 2 (PANK2))
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别名
- PANK2
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背景
- Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).
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分子量
- 62681
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基因ID
- 80025
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NCBI登录号
- NP_079236, NP_705902, NP_705904
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UniProt
- Q9BZ23
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途径
- Ribonucleoside Biosynthetic Process
抗原
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