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STRADA 抗体 (N-Term)

This anti-STRADA antibody is a 兔 多克隆 antibody detecting STRADA in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN391217
发货至: 中国

Quick Overview for STRADA 抗体 (N-Term) (ABIN391217)

抗原

See all STRADA 抗体
STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

适用

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  • 29
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  • 2
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  • 1
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宿主

  • 60
  • 3

克隆类型

  • 61
  • 2
多克隆

标记

  • 29
  • 5
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  • 1
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  • 1
  • 1
  • 1
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This STRADA antibody is un-conjugated

应用范围

  • 56
  • 33
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  • 3
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB8539
  • 抗原表位

    • 15
    • 7
    • 7
    • 6
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    • 4
    • 2
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    • 1
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    AA 12-41, N-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LYK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-41 amino acids from the N-terminal region of human LYK5.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:1000. WB: 1:1000. WB: 1:2000. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

    别名

    LYK5

    背景

    LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.

    分子量

    48369

    基因ID

    92335

    NCBI登录号

    NP_001003786, NP_001003787, NP_001003788, NP_001159441, NP_001159442, NP_699166

    UniProt

    Q7RTN6

    途径

    AMPK Signaling
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