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LRRK1 抗体 (C-Term)

LRRK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6531 unconjugated
产品编号 ABIN391141
发货至: 中国
  • 抗原 See all LRRK1 products
    LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))
    抗原表位
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1981-2015, C-Term
    适用
    • 32
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 30
    • 3
    克隆类型
    • 32
    • 1
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRRK1 antibody is un-conjugated
    应用范围
    • 19
    • 16
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This LRRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1981-2015 amino acids from the C-terminal region of human LRRK1.
    克隆位点
    RB6531
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Toyofuku, Morimoto, Sasawatari, Kumanogoh: "Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation." in: Molecular and cellular biology, Vol. 35, Issue 17, pp. 3044-58, (2015) (PubMed).

  • 抗原
    LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))
    别名
    LRRK1 (LRRK1 产品)
    别名
    RIPK6 antibody, Roco1 antibody, AW319595 antibody, C230002E15Rik antibody, D130026O16Rik antibody, mKIAA1790 antibody, LRRK1 antibody, leucine rich repeat kinase 1 antibody, leucine-rich repeat kinase 1 antibody, leucine-rich repeat kinase 1 L homeolog antibody, leucine-rich repeat serine/threonine-protein kinase 1 antibody, LRRK1 antibody, Lrrk1 antibody, lrrk1.L antibody, lrrk1 antibody, LOC100554060 antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
    分子量
    225393
    基因ID
    79705
    NCBI登录号
    NP_078928
    UniProt
    Q38SD2
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