PNCK 抗体 (C-Term)
(2 references)Quick Overview for PNCK 抗体 (C-Term) (ABIN391139)
抗原
See all PNCK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 314-343, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.
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亚型
- Ig Fraction
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anti-Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK) (AA 1-115) antibody
PNCK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK) (AA 1-121) antibodyPNCK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK) (AA 191-240) antibodyPNCK 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK) (AA 161-210) antibodyPNCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." in: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).
: "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation." in: American journal of physiology. Cell physiology, Vol. 295, Issue 2, pp. C365-77, (2008) (PubMed).
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: "Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." in: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).
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- PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
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别名
- PNCK
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背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
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分子量
- 38500
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基因ID
- 139728
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NCBI登录号
- NP_001034671, NP_001129212
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UniProt
- Q6P2M8
抗原
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