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ADK 抗体 (C-Term)

This anti-ADK antibody is a 兔 多克隆 antibody detecting ADK in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2841255
发货至: 中国

Quick Overview for ADK 抗体 (C-Term) (ABIN2841255)

抗原

See all ADK 抗体
ADK (Adenosine Kinase (ADK))

适用

  • 60
  • 29
  • 13

宿主

  • 54
  • 10

克隆类型

  • 52
  • 11
多克隆

标记

  • 43
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ADK antibody is un-conjugated

应用范围

  • 52
  • 30
  • 24
  • 12
  • 11
  • 9
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB05395
  • 抗原表位

    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 322-352, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Annes, Ryu, Lam, Carolan, Utz, Hollister-Lock, Arvanites, Rubin, Weir, Melton: "Adenosine kinase inhibition selectively promotes rodent and porcine islet ?-cell replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 10, pp. 3915-20, (2012) (PubMed).

  • 抗原

    ADK (Adenosine Kinase (ADK))

    别名

    ADK

    背景

    Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.

    分子量

    40545

    基因ID

    132

    NCBI登录号

    NP_001114, NP_001189378, NP_001189379, NP_006712

    UniProt

    P55263

    途径

    Ribonucleoside Biosynthetic Process
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