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DCK 抗体 (C-Term)

Name: DCK 抗体 (C-Term)
SKU: ABIN391125
Availability: OutOfStock

This anti-DCK antibody is a 兔多克隆 antibody detecting DCK in WB, IF, IP 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 2+ publications.

The anti-DCK Pab (ABIN391125 and ABIN2841251) is used in Western blot to detect DCK in mouse intestine tissue lysate. (DCK 抗体 (C-Term))

DCK Antibody (C-term) B immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (DCK 抗体 (C-Term))

IHC (p)

Deoxycytidine kinase(DCK) immunoprecipitated from H460cells with 7. (DCK 抗体 (C-Term))

Confocal immunofluorescent analysis of DCK Antibody (C-term) (ABIN391125 and ABIN2841251) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (DCK 抗体 (C-Term))

4 images

(2 references)

产品编号 ABIN391125

发货至: 中国

Quick Overview for DCK 抗体 (C-Term) (ABIN391125)

抗原

See all DCK 抗体

DCK (Deoxycytidine Kinase (DCK))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This DCK antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB05276

Discover our top product DCK Primary Antibody

抗原表位
7

6

5

2

2

1

1

1

1

1

1

1

1

1

1
AA 171-200, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This DCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human DCK.

亚型

Ig Fraction
anti-Deoxycytidine Kinase (DCK) (Center) antibody
DCK 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Deoxycytidine Kinase (DCK) antibody
DCK 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Deoxycytidine Kinase (DCK) antibody
DCK 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 16G6 unconjugated

anti-Deoxycytidine Kinase (DCK) antibody
KO Validated DCK 适用: 人 WB, IHC, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Deoxycytidine Kinase (DCK) (AA 161-260) antibody
DCK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated

anti-Deoxycytidine Kinase (DCK) (AA 1-260) antibody
DCK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Deoxycytidine Kinase (DCK) (AA 1-260) antibody
DCK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Deoxycytidine Kinase (DCK) (AA 161-260) antibody
DCK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F10 unconjugated

anti-Deoxycytidine Kinase (DCK) (AA 1-260) antibody
DCK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Deoxycytidine Kinase (DCK) antibody
DCK 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. IP: 1:500~1000. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Hartford, Duan, Delaney, Mi, Kistner, Lamba, Huang, Dolan: "Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity." in: Blood, Vol. 113, Issue 10, pp. 2145-53, (2009) (PubMed).

Lamba, Crews, Pounds, Schuetz, Gresham, Gandhi, Plunkett, Rubnitz, Ribeiro: "Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants." in: The Journal of pharmacology and experimental therapeutics, Vol. 323, Issue 3, pp. 935-45, (2007) (PubMed).
抗原

DCK (Deoxycytidine Kinase (DCK))

别名

DCK

背景

Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.

分子量

30519

基因ID

1633

NCBI登录号

NP_000779

UniProt

P27707