CKM 抗体 (C-Term)
Quick Overview for CKM 抗体 (C-Term) (ABIN391096)
抗原
See all CKM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 283-313, C-Term
-
预测反应
- B, Pig, Rb
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This CKM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the C-terminal region of human CKM.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
-
: "Regulation of sodium-calcium exchanger activity by creatine kinase under energy-compromised conditions." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28275-85, (2010) (PubMed).
-
: "Regulation of sodium-calcium exchanger activity by creatine kinase under energy-compromised conditions." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28275-85, (2010) (PubMed).
-
- CKM (Creatine Kinase, Muscle (CKM))
-
别名
- CKM
-
背景
- Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
-
分子量
- 43101
-
基因ID
- 1158
-
NCBI登录号
- NP_001815
-
UniProt
- P06732
抗原
-