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Ketohexokinase 抗体 (N-Term)

This anti-Ketohexokinase antibody is a 兔 多克隆 antibody detecting Ketohexokinase in WB. Suitable for 人 和 小鼠.
产品编号 ABIN391088
发货至: 中国

Quick Overview for Ketohexokinase 抗体 (N-Term) (ABIN391088)

抗原

See all Ketohexokinase (KHK) 抗体
Ketohexokinase (KHK)

适用

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人, 小鼠

宿主

  • 61
  • 6
  • 1

克隆类型

  • 63
  • 5
多克隆

标记

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  • 1
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This Ketohexokinase antibody is un-conjugated

应用范围

  • 55
  • 29
  • 14
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  • 7
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Western Blotting (WB)

克隆位点

RB05409
  • 抗原表位

    • 15
    • 15
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 18-46, N-Term

    预测反应

    Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This Ketohexokinase (KHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human Ketohexokinase (KHK).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Ketohexokinase (KHK)

    背景

    Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.

    分子量

    32523

    基因ID

    3795

    NCBI登录号

    NP_000212, NP_006479

    UniProt

    P50053
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