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PDPK1 抗体 (N-Term)

Name: PDPK1 抗体 (N-Term)
SKU: ABIN391036
Availability: OutOfStock

PDPK1 适用: 人 WB 宿主: 兔 Polyclonal RB03036 unconjugated

Western blot analysis of PDK1 (arrow) using rabbit polyclonal hPDK1-G14 (ABIN391036 and ABIN2841202). (PDPK1 抗体 (N-Term))

1 image

(1 reference)

产品编号 ABIN391036

发货至: 中国

Datasheet as PDF

抗原 See all PDPK1 抗体

PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
抗原表位
23

19

16

15

15

15

9

7

6

5

5

5

4

4

4

4

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-30, N-Term
适用
181

117

81

11

6

5

4

4

3

2

2

2

2

1

1

1
人
宿主
179

18

1
兔
Compatible Secondaries
克隆类型
166

32
多克隆
标记
88

12

10

9

7

7

7

7

7

7

5

5

5

5

5

3

3

2

2

2
This PDPK1 antibody is un-conjugated
应用范围
153

70

53

53

27

27

12

11

10

8

8

8

3

1

1
Western Blotting (WB)

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PDK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK1.

克隆位点

RB03036

亚型

Ig Fraction

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anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 1-150) antibody
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anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibody
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anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 524-556), (C-Term) antibody
PDPK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 83-338) antibody
PDPK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibody
PDPK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (Internal Region) antibody
PDPK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Xu, Han, Epstein, Liu: "Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets." in: Biochemical and biophysical research communications, Vol. 344, Issue 3, pp. 827-33, (2006) (PubMed).
抗原

PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

别名

PDK1 (PDPK1 产品)

别名

pdpk1 antibody, MGC82080 antibody, PDK1 antibody, PDPK2 antibody, PRO0461 antibody, Pdk1 antibody, zgc:153787 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 antibody, ATPDK1 antibody, AtPDK1 antibody, T32M21.110 antibody, T32M21_110 antibody, zgc:77318 antibody, 3-phosphoinositide dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1 L homeolog antibody, 3-phosphoinositide dependent protein kinase-1 antibody, 3-phosphoinositide dependent protein kinase 1a antibody, 3-phosphoinositide-dependent protein kinase 1 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1b antibody, PDPK1 antibody, pdpk1.L antibody, pdpk1 antibody, Pdpk1 antibody, pdpk1a antibody, LOC100380750 antibody, pdk-1 antibody, PDK1 antibody, pdpk1b antibody

背景

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.

分子量

49244

基因ID

5163

NCBI登录号

NP_002601

UniProt

Q15118

途径

PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals