PDPK1 抗体 (N-Term)
Quick Overview for PDPK1 抗体 (N-Term) (ABIN391036)
抗原
See all PDPK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PDK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets." in: Biochemical and biophysical research communications, Vol. 344, Issue 3, pp. 827-33, (2006) (PubMed).
: "
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Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets." in: Biochemical and biophysical research communications, Vol. 344, Issue 3, pp. 827-33, (2006) (PubMed).
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- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
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别名
- PDK1
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背景
- Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.
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分子量
- 49244
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基因ID
- 5163
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NCBI登录号
- NP_002601
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UniProt
- Q15118
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途径
- PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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