PKC mu 抗体 (N-Term)
(3 references)Quick Overview for PKC mu 抗体 (N-Term) (ABIN391011)
抗原
See all PKC mu (PRKD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 361-389, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PKC mu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-389 amino acids from the N-terminal region of human PKC mu.
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亚型
- Ig Fraction
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anti-Protein Kinase D1 (PRKD1) antibody
PRKD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (pTyr463) antibodyPRKD1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (pSer910) antibodyPRKD1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 314-404) antibodyPRKD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 233-246) antibodyVerified PRKD1 适用: 人 WB, ELISA, IHC, IP 宿主: 山羊 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 383-395) antibodyVerified PRKD1 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 1-912) antibodyPRKD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 171-220) antibodyPRKD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (pSer205) antibodyPRKD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 674-904) antibodyPRKD1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Protein kinase D regulates cofilin activity through p21-activated kinase 4." in: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 34254-61, (2011) (PubMed).
: "Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation." in: Archives of dermatological research, Vol. 300, Issue 3, pp. 139-45, (2008) (PubMed).
: "Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30691-8, (2007) (PubMed).
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: "Protein kinase D regulates cofilin activity through p21-activated kinase 4." in: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 34254-61, (2011) (PubMed).
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- PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
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别名
- PKC mu
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC mu is one of the PKC family members. The protein is a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.
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分子量
- 101704
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基因ID
- 5587
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NCBI登录号
- NP_002733
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UniProt
- Q15139
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途径
- Myometrial Relaxation and Contraction
抗原
-
