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PKC mu 抗体 (N-Term)

Name: PKC mu 抗体 (N-Term)
SKU: ABIN391011
Availability: OutOfStock

Cited in 3+ publications. This 兔多克隆 anti-PKC mu antibody (Clone RB1037) specifically detects PKC mu in WB 和 IHC (p). The antibody is reactive with 人和小鼠 samples.

Western blot analysis of anti-PKC mu N-term Pab (ABIN391011 and ABIN2841184) in mouse kidney lysate. (PKC mu 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (PKC mu 抗体 (N-Term))

IHC (p)

2 images

(3 references)

产品编号 ABIN391011

发货至: 中国

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Quick Overview for PKC mu 抗体 (N-Term) (ABIN391011)

抗原

See all PKC mu (PRKD1) 抗体

PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This PKC mu antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1037

Discover our top product PRKD1 Primary Antibody

抗原表位
19

18

15

15

14

7

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 361-389, N-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PKC mu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-389 amino acids from the N-terminal region of human PKC mu.

亚型

Ig Fraction
anti-Protein Kinase D1 (PRKD1) antibody
PRKD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (pTyr463) antibody
PRKD1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) antibody
PRKD1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4590 unconjugated Recombinant Antibody

anti-Protein Kinase D1 (PRKD1) (pSer910) antibody
PRKD1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (AA 383-395) antibody
Verified PRKD1 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (AA 233-246) antibody
Verified PRKD1 适用: 人 WB, ELISA, IHC, IP 宿主: 山羊 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (AA 314-404) antibody
PRKD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (AA 1-912) antibody
PRKD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (AA 171-220) antibody
PRKD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase D1 (PRKD1) (pSer738), (pSer742) antibody
PRKD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Spratley, Bastea, Döppler, Mizuno, Storz: "Protein kinase D regulates cofilin activity through p21-activated kinase 4." in: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 34254-61, (2011) (PubMed).

Ivanova, Atanasova, Poumay, Mitev: "Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation." in: Archives of dermatological research, Vol. 300, Issue 3, pp. 139-45, (2008) (PubMed).

Wu, Solaro: "Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30691-8, (2007) (PubMed).
抗原

PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

别名

PKC mu

背景

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC mu is one of the PKC family members. The protein is a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.

分子量

101704

基因ID

5587

NCBI登录号

NP_002733

UniProt

Q15139

途径

Myometrial Relaxation and Contraction