PKA C-Alpha,PKA C-beta (AA 9-40), (N-Term) 抗体
The 兔 多克隆 anti-PKA C-Alpha,PKA C-beta antibody (Clone RB1034) (ABIN390999) specifically detects PKA C-Alpha,PKA C-beta in WB 和 IHC (p).
The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN390999
发货至:
中国
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Quick Overview for PKA C-Alpha,PKA C-beta (AA 9-40), (N-Term) 抗体 (ABIN390999)
抗原
PKA C-Alpha,PKA C-beta
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
RB1034
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抗原表位
- AA 9-40, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PKAC alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human PRKACA.
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亚型
- Ig Fraction
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anti-PKA C-Alpha,PKA C-beta antibody
适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PKA C-Alpha,PKA C-beta
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背景
- CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by the PRKACA gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.
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分子量
- 40590
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基因ID
- 5566
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NCBI登录号
- NP_002721, NP_997401
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UniProt
- P17612
抗原
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