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GRK5 抗体 (C-Term)

This anti-GRK5 antibody is a 兔 多克隆 antibody detecting GRK5 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN390988
发货至: 中国

Quick Overview for GRK5 抗体 (C-Term) (ABIN390988)

抗原

See all GRK5 抗体
GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

适用

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人, 小鼠

宿主

  • 44
  • 2
  • 1

克隆类型

  • 45
  • 2
多克隆

标记

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This GRK5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB0903
  • 抗原表位

    • 7
    • 7
    • 4
    • 4
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 559-590, C-Term

    预测反应

    B

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This GRK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-590 amino acids from the C-terminal region of human GRK5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

    别名

    GRK5

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

    分子量

    67787

    基因ID

    2869

    NCBI登录号

    NP_005299

    UniProt

    P34947

    途径

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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