AD_K2 (AA 633-660), (C-Term) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, 猴 和 小鼠. This Primary Antibody has been cited in 2+ publications.
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(2 references)Quick Overview for AD_K2 (AA 633-660), (C-Term) 抗体 (ABIN390986)
抗原
AD_K2
适用
人, 猴, 小鼠
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
克隆位点
RB00896
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抗原表位
- AA 633-660, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This AD_K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 633-660 amino acids from the C-terminal region of human AD_K2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis." in: PLoS ONE, Vol. 11, Issue 4, pp. e0152856, (2016) (PubMed).
: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, (2009) (PubMed).
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: "G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis." in: PLoS ONE, Vol. 11, Issue 4, pp. e0152856, (2016) (PubMed).
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- AD_K2
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背景
- The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the ADRBK2 enzyme, also known as GRK3, has 85 % amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95 % similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
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分子量
- 79710
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基因ID
- 157
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NCBI登录号
- NP_005151
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UniProt
- P35626
抗原
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