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Aurora Kinase C 抗体 (AA 115-145)

Cited in 1 publication. This 兔 多克隆 anti-Aurora Kinase C antibody (Clone RB6822) specifically detects Aurora Kinase C in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN390979
发货至: 中国
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Quick Overview for Aurora Kinase C 抗体 (AA 115-145) (ABIN390979)

抗原

See all Aurora Kinase C (AURKC) 抗体
Aurora Kinase C (AURKC)

适用

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人, 小鼠

宿主

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克隆类型

  • 67
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多克隆

标记

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This Aurora Kinase C antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB6822
  • 抗原表位

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    AA 115-145

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the Central region of human Aurora-C.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Burum-Auensen, Skotheim, Schjølberg, Røislien, Lothe, Clausen: "Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors." in: Journal of carcinogenesis, Vol. 9, pp. 1, (2010) (PubMed).

  • 抗原

    Aurora Kinase C (AURKC)

    别名

    Aurora-C

    背景

    Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

    分子量

    35591

    基因ID

    6795

    NCBI登录号

    NP_001015878, NP_001015879, NP_003151

    UniProt

    Q9UQB9

    途径

    Cell Division Cycle, Maintenance of Protein Location
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