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MTM1 抗体 (C-Term)

This anti-MTM1 antibody is a 兔 多克隆 antibody detecting MTM1 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN390784
发货至: 中国

Quick Overview for MTM1 抗体 (C-Term) (ABIN390784)

抗原

See all MTM1 抗体
MTM1 (Myotubularin 1 (MTM1))

适用

  • 44
  • 37
  • 25
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 4
  • 1

克隆类型

  • 43
  • 3
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MTM1 antibody is un-conjugated

应用范围

  • 40
  • 14
  • 14
  • 13
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB0856
  • 抗原表位

    • 16
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 566-594, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This MTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 566-594 amino acids from the C-terminal region of human MTM1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Jian, Cheng, Jiang, Deng, Hu, Zhang: "A cDNA-based random RNA interference library for functional genetic screens in embryonic stem cells." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 8, pp. 1904-12, (2007) (PubMed).

  • 抗原

    MTM1 (Myotubularin 1 (MTM1))

    别名

    MTM1

    背景

    MTM1 is a member of a protein family that encodes tyrosine phosphatases. Myotubularin is required for muscle cell differentiation and mutations in MTM1 have been identified as being responsible for X-linked myotubular myopathy. MTM1 is a potent phosphatidylinositol 3-phosphate phosphatase (PI(3)P). Mutations in the MTM1 gene that cause human myotubular myopathy dramatically reduce the ability of the phosphatase to dephosphorylate PI(3)P. The findings provided evidence that myotubularin exerts its effects during myogenesis by regulating the cellular levels of the inositol lipid PI(3)P.

    分子量

    69932

    基因ID

    4534

    NCBI登录号

    NP_000243

    UniProt

    Q13496

    途径

    Inositol Metabolic Process, Skeletal Muscle Fiber Development
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