MTBP 抗体 (C-Term)
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北京 101111
Quick Overview for MTBP 抗体 (C-Term) (ABIN390601)
抗原
See all MTBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 853-881, C-Term
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预测反应
- M
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This MTBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 853-881 amino acids from the C-terminal region of human MTBP.
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亚型
- Ig Fraction
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anti-MDM2 Binding Protein (MTBP) antibody
MTBP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibodyMTBP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 23-350) antibodyMTBP 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 122-139) antibodyMTBP 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 122-139), (Middle Region) antibodyMTBP 适用: 人 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- MTBP (MDM2 Binding Protein (MTBP))
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别名
- MTBP
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背景
- MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
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分子量
- 102193
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基因ID
- 27085
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NCBI登录号
- NP_071328
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UniProt
- Q96DY7
抗原
-
