Caldesmon 抗体 (AA 428-457)
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Quick Overview for Caldesmon 抗体 (AA 428-457) (ABIN390542)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 428-457
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This CALD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- CALD1
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背景
- CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.
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分子量
- 93231
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基因ID
- 800
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NCBI登录号
- NP_004333, NP_149129, NP_149130, NP_149131, NP_149347
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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