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SUV420H2/KMT5C 抗体 (AA 187-214)

Cited in 1 publication. This anti-SUV420H2/KMT5C antibody is a 兔 多克隆 antibody detecting SUV420H2/KMT5C in WB 和 FACS. Suitable for 小鼠 和 人.
产品编号 ABIN390405
发货至: 中国
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Quick Overview for SUV420H2/KMT5C 抗体 (AA 187-214) (ABIN390405)

抗原

See all SUV420H2/KMT5C (SUV420H2) 抗体
SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

适用

  • 15
  • 14
  • 2
  • 1
  • 1
  • 1
小鼠, 人

宿主

  • 22
  • 2

克隆类型

  • 20
  • 3
  • 1
多克隆

标记

  • 15
  • 4
  • 3
  • 1
  • 1
This SUV420H2/KMT5C antibody is un-conjugated

应用范围

  • 17
  • 9
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB19392
  • 抗原表位

    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 187-214

    预测反应

    Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids of human SUV4-20H2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Boonsanay, Zhang, Georgieva, Kostin, Qi, Yuan, Zhou, Braun: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." in: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).

  • 抗原

    SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

    别名

    SUV4-20H2

    背景

    SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

    分子量

    52113

    基因ID

    84787

    NCBI登录号

    NP_116090

    UniProt

    Q86Y97
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