SUV420H2/KMT5C 抗体 (AA 187-214)
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北京 101111
Quick Overview for SUV420H2/KMT5C 抗体 (AA 187-214) (ABIN390405)
抗原
See all SUV420H2/KMT5C (SUV420H2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 187-214
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids of human SUV4-20H2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." in: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).
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: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." in: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).
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- SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))
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别名
- SUV4-20H2
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背景
- SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
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分子量
- 52113
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基因ID
- 84787
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NCBI登录号
- NP_116090
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UniProt
- Q86Y97
抗原
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