SNCAIP 抗体 (C-Term)
Quick Overview for SNCAIP 抗体 (C-Term) (ABIN390382)
抗原
See all SNCAIP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 593-622, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP).
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亚型
- Ig Fraction
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anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 309-553) antibody
SNCAIP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 51-150) antibodySNCAIP 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 1-603) antibodySNCAIP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 206-309) antibodySNCAIP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (C-Term) antibodySNCAIP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (C-Term) antibodySNCAIP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 1-603) antibodySNCAIP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 766-963) antibodySNCAIP 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha Interacting Protein (SNCAIP) (AA 593-622), (C-Term) antibodySNCAIP 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
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别名
- Synphilin-1 (SNCAIP)
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背景
- Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with its human counterpart, especially in regions containing ankyrin-like motifs and the coiled-coil domain. Expression of mouse synphilin-1 in tissues is similar to its human counterpart. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and that Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson disease
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分子量
- 100409
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基因ID
- 9627
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NCBI登录号
- NP_001229864, NP_005451
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UniProt
- Q9Y6H5
抗原
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