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Glypican 3 抗体 (N-Term)

This anti-Glypican 3 antibody is a 兔 多克隆 antibody detecting Glypican 3 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN390317
发货至: 中国

Quick Overview for Glypican 3 抗体 (N-Term) (ABIN390317)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

适用

  • 184
  • 64
  • 49
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 110
  • 73
  • 5
  • 2
  • 1
  • 1

克隆类型

  • 97
  • 87
  • 5
多克隆

标记

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  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Glypican 3 antibody is un-conjugated

应用范围

  • 97
  • 86
  • 85
  • 69
  • 58
  • 30
  • 26
  • 17
  • 15
  • 15
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB05031
  • 抗原表位

    • 22
    • 16
    • 12
    • 8
    • 7
    • 6
    • 6
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    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-50, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This Glypican 3 (GPC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human Glypican 3 (GPC3).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Han, Ma, Zhao, Zhao, Batista, Zhou, Zhou, Yang, Wang, Bi, Xia, Bai, Garkavtsev, Zhang: "Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." in: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).

  • 抗原

    Glypican 3 (GPC3)

    背景

    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.

    分子量

    65563

    基因ID

    2719

    NCBI登录号

    NP_001158089, NP_001158091, NP_004475

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
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