HIRA 抗体 (AA 431-461)
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北京 101111
Quick Overview for HIRA 抗体 (AA 431-461) (ABIN390223)
抗原
See all HIRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 431-461
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预测反应
- C, M, X
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This HIRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-461 amino acids from the Central region of human HIRA.
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亚型
- Ig Fraction
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anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 250-550) antibody
HIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-1017) antibodyHIRA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (pThr555) antibodyHIRA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 374C6a unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 251-350) antibodyHIRA 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: Saccharomyces cerevisiae WB 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal WC15 unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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别名
- HIRA
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背景
- HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
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分子量
- 111835
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基因ID
- 7290
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NCBI登录号
- NP_003316
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UniProt
- P54198
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途径
- Chromatin Binding
抗原
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