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SIRT7 抗体 (C-Term)

This anti-SIRT7 antibody is a 兔 多克隆 antibody detecting SIRT7 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN390182
发货至: 中国

Quick Overview for SIRT7 抗体 (C-Term) (ABIN390182)

抗原

See all SIRT7 抗体
SIRT7 (Sirtuin 7 (SIRT7))

适用

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宿主

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克隆类型

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  • 6
多克隆

标记

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This SIRT7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1973
  • 抗原表位

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    AA 331-360, C-Term

    预测反应

    B, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SIRT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human SIRT7.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Wang, Yi, Li, Cai, He, Ni, Zhou, Cheng, Jin, Fan, Qiu: "Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection." in: BMC cancer, Vol. 14, pp. 297, (2014) (PubMed).

    Sestito, Madonna, Scarponi, Cianfarani, Failla, Cavani, Girolomoni, Albanesi: "STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 3, pp. 916-27, (2011) (PubMed).

    Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: "Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer." in: Cancer, Vol. 117, Issue 8, pp. 1670-8, (2011) (PubMed).

  • 抗原

    SIRT7 (Sirtuin 7 (SIRT7))

    别名

    SIRT7

    背景

    SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

    分子量

    44898

    基因ID

    51547

    NCBI登录号

    NP_057622

    UniProt

    Q9NRC8
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