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SIRT6 抗体 (C-Term)

Name: SIRT6 抗体 (C-Term)
SKU: ABIN2840672
Availability: OutOfStock

This anti-SIRT6 antibody is a 兔多克隆 antibody detecting SIRT6 in WB 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of SIRT6 Antibody (C-term) (ABIN390181 and ABIN2840672) in mouse stomach tissue lysates (35 μg/lane). (SIRT6 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (SIRT6 抗体 (C-Term))

IHC (p)

2 images

(4 references)

产品编号 ABIN2840672

发货至: 中国

Quick Overview for SIRT6 抗体 (C-Term) (ABIN2840672)

抗原

See all SIRT6 抗体

SIRT6 (Sirtuin 6 (SIRT6))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This SIRT6 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB2109

Discover our top product SIRT6 Primary Antibody

抗原表位
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2

2

2

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1

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1
AA 290-319, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the C-terminal region of human SIRT6.

亚型

Ig Fraction
anti-Sirtuin 6 (SIRT6) (AA 1-334) antibody
SIRT6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 6 (SIRT6) (AA 141-250) antibody
SIRT6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2G1H1 unconjugated

anti-Sirtuin 6 (SIRT6) antibody
SIRT6 适用: 人, 小鼠, 大鼠, 猴 WB, IP, IF 宿主: 小鼠 Monoclonal 6C9-D10-D3 unconjugated

anti-Sirtuin 6 (SIRT6) (Middle Region) antibody
SIRT6 适用: 人, 大鼠, 犬, Cow WB, IP, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 6 (SIRT6) (N-Term) antibody
SIRT6 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 6 (SIRT6) (AA 35-274) antibody
SIRT6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 6 (SIRT6) (C-Term) antibody
SIRT6 适用: 人, 大鼠, 犬, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 6 (SIRT6) (AA 56-105) antibody
SIRT6 适用: 人, 小鼠, 犬, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 6 (SIRT6) (AA 141-250) antibody
SIRT6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Sirtuin 6 (SIRT6) (C-Term) antibody
SIRT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:500. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Li, Shi, Yang, Yan, Zhang, Yang, He, Li, Yi, Sun, Liang, Cheng, Shi, Shang, Yu: "SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." in: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).

Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).

Wu, Liu, Fu, Liu, Zhou: "Direct evidence of sirtuin downregulation in the liver of non-alcoholic fatty liver disease patients." in: Annals of clinical and laboratory science, Vol. 44, Issue 4, pp. 410-8, (2014) (PubMed).

Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: "Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer." in: Cancer, Vol. 117, Issue 8, pp. 1670-8, (2011) (PubMed).
抗原

SIRT6 (Sirtuin 6 (SIRT6))

别名

SIRT6

背景

SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

分子量

39119

基因ID

51548

NCBI登录号

NP_001180214, NP_057623

UniProt

Q8N6T7