OASL 抗体 (C-Term)
(3 references)Quick Overview for OASL 抗体 (C-Term) (ABIN390168)
抗原
See all OASL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 484-514, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This OASL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human OASL.
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亚型
- Ig Fraction
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anti-2'-5'-Oligoadenylate Synthetase-Like (OASL) (AA 1-50) antibody
OASL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase-Like (OASL) (AA 420-469) antibodyOASL 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase-Like (OASL) (C-Term) antibodyOASL 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase-Like (OASL) (AA 2-244) antibodyOASL 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-2'-5'-Oligoadenylate Synthetase-Like (OASL) (C-Term) antibodyOASL 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 12, pp. 5933-42, (2014) (PubMed).
: "Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1476-85, (2013) (PubMed).
: "2',5'-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro." in: Biochemical and biophysical research communications, Vol. 392, Issue 3, pp. 397-402, (2010) (PubMed).
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: "Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 12, pp. 5933-42, (2014) (PubMed).
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- OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))
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别名
- OASL
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背景
- 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
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分子量
- 59226
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基因ID
- 8638
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NCBI登录号
- NP_001248754, NP_003724, NP_937856
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UniProt
- Q15646
抗原
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