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MLLT1 抗体 (C-Term)

Cited in 1 publication. The 兔 多克隆 anti-MLLT1 antibody (Clone RB1927-1928) (ABIN390126) specifically detects MLLT1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN390126
发货至: 中国
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Quick Overview for MLLT1 抗体 (C-Term) (ABIN390126)

抗原

See all MLLT1 抗体
MLLT1 (MLLT1, super elongation complex subunit (MLLT1))

适用

  • 19
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宿主

  • 16
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克隆类型

  • 17
  • 2
多克隆

标记

  • 14
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This MLLT1 antibody is un-conjugated

应用范围

  • 16
  • 8
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Western Blotting (WB)

克隆位点

RB1927-1928
  • 抗原表位

    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
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    AA 523-552, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:2000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Bitoun, Oliver, Davies: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." in: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).

  • 抗原

    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))

    别名

    MLLT1

    背景

    Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.

    分子量

    62056

    基因ID

    4298

    NCBI登录号

    NP_005925

    UniProt

    Q03111
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