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CRY2 抗体 (C-Term)

Name: CRY2 抗体 (C-Term)
SKU: ABIN390080
Availability: OutOfStock

This anti-CRY2 antibody is a 兔多克隆 antibody detecting CRY2 in WB 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 1 publication.

Western blot analysis of lysates from human heart, skeletal muscle and liver tissue lysate (from left to right), using Cry2 Antibody A. (CRY2 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (CRY2 抗体 (C-Term))

IHC (p)

Western blot analysis of lysates from human skeletal muscle and human heart tissue (from left to right), using Cry2 Antibody A. (CRY2 抗体 (C-Term))

3 images

(1 reference)

产品编号 ABIN390080

发货至: 中国

Datasheet as PDF

Quick Overview for CRY2 抗体 (C-Term) (ABIN390080)

抗原

See all CRY2 抗体

CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This CRY2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1846

Discover our top product CRY2 Primary Antibody

抗原表位
6

5

2

2

2

1

1

1

1

1
AA 564-593, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This Cry2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 564-593 amino acids from the C-terminal region of human Cry2.

亚型

Ig Fraction
anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 141-231) antibody
CRY2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H4 unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 434-593) antibody
CRY2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 1-593) antibody
CRY2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 171-200), (N-Term) antibody
CRY2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (N-Term) antibody
CRY2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) antibody
CRY2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1819CT334-92-36-9 unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 179-228) antibody
CRY2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (AA 455-614) antibody
CRY2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) (C-Term) antibody
CRY2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Cryptochrome 2 (Photolyase-Like) (CRY2) antibody
CRY2 适用: 人 WB 宿主: 小鼠 Monoclonal Q3W3 unconjugated

应用备注

WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Wang, Wang, Liu, Liu, Tay, Walsh, Yang, Wu: "CRISPR/Cas9 mediated genome editing of Helicoverpa armigera with mutations of an ABC transporter gene HaABCA2 confers resistance to Bacillus thuringiensis Cry2A toxins." in: Insect biochemistry and molecular biology, Vol. 87, pp. 147-153, (2017) (PubMed).
抗原

CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

别名

Cry2

背景

Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock. The central ?gears?driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop. Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases. In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function. Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM. They seem to act as light-independent components of the circadian clock and likely regulate Per1 transcriptional cycling via interactions with both the activator and its feedback inhibitors. Mutant mice not expressing the Cry1 or Cry2 protein display accelerated and delayed periodicity of locomotor activity, respectively. It appears that the combination of both proteins working together is essential to synchronize the organism to circadian phases. A critical balance between Cry1 and Cry2 is required for proper clock function, in complete darkness, double-mutant mice present with instantaneous arrhythmicity, indicating the absence of an internal circadian clock.

分子量

66947

基因ID

1408

NCBI登录号

NP_001120929, NP_066940

UniProt

Q49AN0

途径

Response to Water Deprivation, Protein targeting to Nucleus