ANTXR1 抗体 (pTyr425)
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北京 101111
Quick Overview for ANTXR1 抗体 (pTyr425) (ABIN389986)
抗原
See all ANTXR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr425
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.
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亚型
- Ig Fraction
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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别名
- ANTXR1
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背景
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
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分子量
- 62789
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基因ID
- 84168
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NCBI登录号
- NP_060623, NP_115584, NP_444262
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UniProt
- Q9H6X2
抗原
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