TNK2 抗体 (pTyr518)
Our Local Distributor
北京 101111
Quick Overview for TNK2 抗体 (pTyr518) (ABIN389970)
抗原
See all TNK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pTyr518
-
预测反应
- B
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This ACK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- DB: 1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
-
别名
- ACK1
-
背景
- ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
-
分子量
- 114569
-
基因ID
- 10188
-
NCBI登录号
- NP_001010938, NP_005772
-
UniProt
- Q07912
抗原
-