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YES1/SRC (pTyr530) 抗体

适用: 人 DB, IHC (p) 宿主: 兔 Polyclonal RB05974 unconjugated
产品编号 ABIN389661
发货至: 中国
  • 抗原
    YES1/SRC
    抗原表位
    pTyr530
    适用
    宿主
    克隆类型
    多克隆
    应用范围
    Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    C, Zf, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SRC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y530 of human SRC.
    克隆位点
    RB05974
    亚型
    Ig Fraction
  • 应用备注
    IHC-P: 1:50~100. DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Miller, Morton, Pinese, Saturno, Jamieson, McGhee, Timpson, Leach, McGarry, Shanks, Bailey, Chang, Oien, Karim, Au, Steele, Carter, McKay, Anderson, Evans, Marais, Springer, Biankin, Erler, Sansom: "Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy." in: EMBO molecular medicine, Vol. 7, Issue 8, pp. 1063-76, (2015) (PubMed).

    Varrin-Doyer, Vincent, Cavagna, Auvergnon, Noraz, Rogemond, Honnorat, Moradi-Améli, Giraudon: "Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration." in: The Journal of biological chemistry, Vol. 284, Issue 19, pp. 13265-76, (2009) (PubMed).

  • 抗原
    YES1/SRC
    背景
    This protein has tyrosine kinase activity and belongs to the src family of proteins. The YES1 gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene.
    基因ID
    6714
    NCBI登录号
    NP_005408, NP_938033
    UniProt
    P12931, P07947
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