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YES1/SRC (pTyr530) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in DB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN389661
发货至: 中国

Quick Overview for YES1/SRC (pTyr530) 抗体 (ABIN389661)

抗原

YES1/SRC

适用

宿主

克隆类型

多克隆

应用范围

Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB05974
  • 抗原表位

    pTyr530

    预测反应

    C, Zf, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SRC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y530 of human SRC.

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:50~100. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

    有效期

    6 months
  • Miller, Morton, Pinese, Saturno, Jamieson, McGhee, Timpson, Leach, McGarry, Shanks, Bailey, Chang, Oien, Karim, Au, Steele, Carter, McKay, Anderson, Evans, Marais, Springer, Biankin, Erler, Sansom: "Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy." in: EMBO molecular medicine, Vol. 7, Issue 8, pp. 1063-76, (2015) (PubMed).

    Varrin-Doyer, Vincent, Cavagna, Auvergnon, Noraz, Rogemond, Honnorat, Moradi-Améli, Giraudon: "Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration." in: The Journal of biological chemistry, Vol. 284, Issue 19, pp. 13265-76, (2009) (PubMed).

  • 抗原

    YES1/SRC

    背景

    This protein has tyrosine kinase activity and belongs to the src family of proteins. The YES1 gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene.

    基因ID

    6714

    NCBI登录号

    NP_005408, NP_938033

    UniProt

    P12931, P07947
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