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MYT1 抗体 (pThr495)

This 兔 多克隆 antibody specifically detects MYT1 in WB, IHC (p) 和 DB. It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN389599
发货至: 中国
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Quick Overview for MYT1 抗体 (pThr495) (ABIN389599)

抗原

See all MYT1 抗体
MYT1 (Myelin Transcription Factor 1 (MYT1))

适用

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宿主

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克隆类型

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  • 1
多克隆

标记

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This MYT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

克隆位点

RB7898
  • 抗原表位

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    pThr495

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MYT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T495 of human MYT1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Mac?rek, Lindqvist, Lim, Lampson, Klompmaker, Freire, Clouin, Taylor, Yaffe, Medema: "Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery." in: Nature, Vol. 455, Issue 7209, pp. 119-23, (2008) (PubMed).

  • 抗原

    MYT1 (Myelin Transcription Factor 1 (MYT1))

    别名

    MYT1

    背景

    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

    分子量

    54521

    基因ID

    9088

    NCBI登录号

    NP_001245379, NP_001245380, NP_004194, NP_872629

    UniProt

    Q99640

    途径

    Cell Division Cycle
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