MYT1 抗体 (pThr495)
Quick Overview for MYT1 抗体 (pThr495) (ABIN389599)
抗原
See all MYT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pThr495
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This MYT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T495 of human MYT1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000. IHC-P: 1:50~100. DB: 1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
-
: "Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery." in: Nature, Vol. 455, Issue 7209, pp. 119-23, (2008) (PubMed).
-
: "Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery." in: Nature, Vol. 455, Issue 7209, pp. 119-23, (2008) (PubMed).
-
- MYT1 (Myelin Transcription Factor 1 (MYT1))
-
别名
- MYT1
-
背景
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
-
分子量
- 54521
-
基因ID
- 9088
-
NCBI登录号
- NP_001245379, NP_001245380, NP_004194, NP_872629
-
UniProt
- Q99640
-
途径
- Cell Division Cycle
抗原
-