FGFR (pTyr766) 抗体
There is 1 publication for this product available. The 兔 多克隆 anti-FGFR antibody is suitable to detect FGFR in samples from 人 和 小鼠. It has been validated for WB 和 IHC (p).
(1 reference)
产品编号 ABIN389561
发货至:
中国
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Quick Overview for FGFR (pTyr766) 抗体 (ABIN389561)
抗原
FGFR
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
RB5784
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抗原表位
- pTyr766
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预测反应
- C, Rat, Zf
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y766 of human FGFR.
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亚型
- Ig Fraction
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anti-FGFR (pTyr766) antibody
适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in ..." in: Blood, Vol. 112, Issue 2, pp. 295-307, (2008) (PubMed).
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: "PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in ..." in: Blood, Vol. 112, Issue 2, pp. 295-307, (2008) (PubMed).
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- FGFR
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背景
- FGFR is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
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分子量
- 91868
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基因ID
- 2260
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NCBI登录号
- NP_001167534, NP_001167535, NP_001167536, NP_001167537, NP_001167538, NP_056934, NP_075593, NP_075594, NP_075598
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UniProt
- P11362
抗原
-
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