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PFDN6 抗体 (N-Term)

This anti-PFDN6 antibody is a 兔 多克隆 antibody detecting PFDN6 in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN389346
发货至: 中国

Quick Overview for PFDN6 抗体 (N-Term) (ABIN389346)

抗原

See all PFDN6 抗体
PFDN6 (Prefoldin Subunit 6 (PFDN6))

适用

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宿主

  • 16
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克隆类型

  • 16
  • 1
多克隆

标记

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This PFDN6 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB17559
  • 抗原表位

    • 6
    • 2
    • 1
    • 1
    AA 6-34, N-Term

    预测反应

    B, M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PFDN6.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Tashiro, Zako, Muto, Itoo, Sörgjerd, Terada, Abe, Miyazawa, Kitamura, Kitaura, Kubota, Maeda, Momoi, Iguchi-Ariga, Kinjo, Ariga: "Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).

    Abe, Takahashi-Niki, Takekoshi, Shimizu, Kitaura, Maita, Iguchi-Ariga, Ariga: "Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation." in: The Journal of biological chemistry, Vol. 288, Issue 39, pp. 27764-76, (2013) (PubMed).

    Miyazawa, Tashiro, Kitaura, Maita, Suto, Iguchi-Ariga, Ariga: "Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19191-203, (2011) (PubMed).

  • 抗原

    PFDN6 (Prefoldin Subunit 6 (PFDN6))

    别名

    PFDN6

    背景

    PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

    分子量

    14583

    基因ID

    10471

    NCBI登录号

    NP_001172110, NP_001252524, NP_001252525, NP_055075

    UniProt

    O15212

    途径

    Unfolded Protein Response
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