SNURF 抗体 (AA 4-32)
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Quick Overview for SNURF 抗体 (AA 4-32) (ABIN389318)
抗原
See all SNURF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 4-32
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预测反应
- B, M, Rb
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SNURF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the Central region of human SNURF.
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亚型
- Ig Fraction
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SNURF (SNRPN Upstream Reading Frame (SNURF))
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别名
- SNURF
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背景
- SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.
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分子量
- 8412
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基因ID
- 8926
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NCBI登录号
- NP_005669, NP_073715
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UniProt
- Q9Y675
抗原
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