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Doublecortin 抗体 (AA 107-137)

This anti-Doublecortin antibody is a 兔 多克隆 antibody detecting Doublecortin in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN389254
发货至: 中国

Quick Overview for Doublecortin 抗体 (AA 107-137) (ABIN389254)

抗原

See all Doublecortin (DCX) 抗体
Doublecortin (DCX)

适用

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宿主

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克隆类型

  • 91
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多克隆

标记

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This Doublecortin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB15193
  • 抗原表位

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    AA 107-137

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-137 amino acids from human DCX.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Doublecortin (DCX)

    别名

    DCX

    背景

    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

    分子量

    40574

    基因ID

    1641

    NCBI登录号

    NP_000546, NP_835364, NP_835365, NP_835366

    UniProt

    O43602
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