CBX4 抗体 (C-Term)
(2 references)Quick Overview for CBX4 抗体 (C-Term) (ABIN389087)
抗原
See all CBX4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 410-437, C-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human CBX4.
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亚型
- Ig Fraction
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anti-Chromobox Homolog 4 (CBX4) (AA 397-514) antibody
CBX4 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6C5G3 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-160) antibodyCBX4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-500) antibodyCBX4 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-560) antibodyCBX4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-290) antibodyCBX4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (N-Term) antibodyCBX4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 80-110), (N-Term) antibodyCBX4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2931 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 53-102) antibodyCBX4 适用: 人, 小鼠, 犬, Cow, 豚鼠, 兔, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 150-200) antibodyCBX4 适用: 人, 小鼠, 犬, Cow, 豚鼠, 兔, Pig IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) antibodyCBX4 适用: 人, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 43, pp. 16572-7, (2008) (PubMed).
: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).
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: "Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 43, pp. 16572-7, (2008) (PubMed).
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- CBX4 (Chromobox Homolog 4 (CBX4))
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别名
- CBX4
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背景
- Chromobox homolog 4 (CBX4 or Pc2) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system that is responsible for the inheritance of gene activity by progeny cells. CBX4 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain. It was reported that Pc2 is involved in sumoylation process by recruiting SUMO E1 and E2, and Pc2 is actually SUMO E3 during sumoylation events. CBX4 expression is ubiquitous.
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分子量
- 61368
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基因ID
- 8535
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NCBI登录号
- NP_003646
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UniProt
- O00257
抗原
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