GPLD1 抗体 (C-Term)
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Quick Overview for GPLD1 抗体 (C-Term) (ABIN389063)
抗原
See all GPLD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 679-709, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This GPLD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-709 amino acids from the C-terminal region of human GPLD1.
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亚型
- Ig Fraction
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anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 496-840) antibody
GPLD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 24-160) antibodyGPLD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) antibodyGPLD1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 310-565) antibodyGPLD1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (Internal Region) antibodyGPLD1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 1-176) antibodyGPLD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- GPLD1 (Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1))
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别名
- GPLD1
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背景
- GPLD1 is expressed in numerous tissues and cells and specifically cleaves GPI-anchored proteins. Liver has the highest level of GPI-PLD expression and is the primary organ contributing to GPLD1 in the serum. GPLD1 is abundant in serum in which it associates with polipoproteins AI and AIV. Increased serum GPLD1 is associated with insulin resistance and elevated serum triglycerides. Many surface proteins are attached to eukaryotic cell membranes via glycosylphosphatidylinositol (GPI) anchors that are covalently bound to the C-terminus of the protein and cleavage of the GPI moiety by GPLD1, only enzyme known that cleavage GPI anchor, may represent a means of regulating attachment of these proteins to the cell surface, or alternatively, their release into the extracellular environment.
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分子量
- 92336
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基因ID
- 2822
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NCBI登录号
- NP_001494
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UniProt
- P80108
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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