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FNTA 抗体 (AA 88-118)

This 兔 多克隆 anti-FNTA antibody (Clone RB4792) specifically detects FNTA in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN389057
发货至: 中国
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Quick Overview for FNTA 抗体 (AA 88-118) (ABIN389057)

抗原

See all FNTA 抗体
FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

适用

  • 56
  • 30
  • 21
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 54
  • 2

克隆类型

  • 44
  • 12
多克隆

标记

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  • 2
  • 2
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  • 2
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FNTA antibody is un-conjugated

应用范围

  • 48
  • 13
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  • 11
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  • 6
  • 2
  • 2
  • 2
  • 1
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  • 1
Western Blotting (WB)

克隆位点

RB4792
  • 抗原表位

    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 88-118

    预测反应

    B, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

    别名

    FNTA

    背景

    FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

    分子量

    44409

    基因ID

    2339

    NCBI登录号

    NP_002018

    UniProt

    P49354

    途径

    Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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