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GGPS1 抗体 (C-Term)

This anti-GGPS1 antibody is a 兔 多克隆 antibody detecting GGPS1 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN389056
发货至: 中国

Quick Overview for GGPS1 抗体 (C-Term) (ABIN389056)

抗原

See all GGPS1 抗体
GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

适用

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人, 小鼠

宿主

  • 68
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克隆类型

  • 70
  • 4
多克隆

标记

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This GGPS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4789
  • 抗原表位

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    AA 270-300, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human GGPS1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Jiang, Backlund, Wassif, Yergey, Porter: "Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 7, pp. 1461-75, (2010) (PubMed).

  • 抗原

    GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

    别名

    GGPS1

    背景

    Geranylgeranyl diphosphate (GGPP) synthase (GGPS) catalyzes the synthesis of GGPP, a molecule responsible for the C20-prenylation of protein and for the regulation of a nuclear hormone receptor. The deduced 300-amino acid human protein contains 5 conserved domains consistent with prenyltransferases. Recombinant GGPS shows enzymatic properties associated with the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. Mouse GGPS is regulated in several tissues in obesity and is induced during adipocyte differentiation. GGPS is increased 5- to 20-fold in skeletal muscle, liver, and fat of ob/ob mice. Western blot analysis detects a 2-fold overexpression of protein in muscle and fat but not in liver. Differentiation of mouse fibroblasts into adipocytes induces GGPS expression more than 20-fold.

    分子量

    34871

    基因ID

    9453

    NCBI登录号

    NP_001032354

    UniProt

    O95749
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