FDFT1 抗体 (AA 140-170)
(3 references)Quick Overview for FDFT1 抗体 (AA 140-170) (ABIN389052)
抗原
See all FDFT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 140-170
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-170 amino acids from the Central region of human FDFT1.
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亚型
- Ig Fraction
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anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 269-417) antibody
FDFT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 适用: 人, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-260) antibodyFDFT1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 2-417) antibodyFDFT1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 10H12 unconjugated Recombinant Antibody
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-30), (N-Term) antibodyFDFT1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB04780 unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
: "Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches." in: Proteomics, Vol. 10, Issue 1, pp. 99-114, (2010) (PubMed).
: "Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells." in: Lipids, Vol. 44, Issue 8, pp. 673-83, (2009) (PubMed).
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: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
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- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
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别名
- FDFT1
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背景
- FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
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分子量
- 48115
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基因ID
- 2222
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NCBI登录号
- NP_004453
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UniProt
- P37268
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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