AGL 抗体 (C-Term)
(6 references)-
- 抗原 See all AGL 抗体
- AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))
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抗原表位
- AA 1479-1510, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AGL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This AGL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1479-1510 amino acids from the C-terminal region of human AGL.
- 克隆位点
- RB4978
- 亚型
- Ig Fraction
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anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (AA 1479-1510) antibody
AGL 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (AA 357-387) antibodyAGL 适用: 人 WB, IF 宿主: 兔 Polyclonal RB4976 unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (N-Term) antibodyAGL 适用: 人 WB, IF 宿主: 兔 Polyclonal RB5106 unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (AA 1-1532) antibodyAGL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) antibodyAGL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (AA 1217-1378) antibodyAGL 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (AA 1233-1532) antibodyAGL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) antibodyAGL 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (AA 1487-1516), (C-Term) antibodyAGL 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF: 1:10~50. IF: 1:10~50. WB: 1:1000. WB: 1:8000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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-
: "Loss of glycogen debranching enzyme AGL drives bladder tumor growth via induction of hyaluronic acid synthesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2015) (PubMed).
: "Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase." in: Molecular neurobiology, Vol. 49, Issue 2, pp. 645-57, (2014) (PubMed).
: "Anti-retinal antibodies in patients with macular telangiectasia type 2." in: Investigative ophthalmology & visual science, Vol. 54, Issue 8, pp. 5675-83, (2013) (PubMed).
: "Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25372-81, (2010) (PubMed).
: "Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis." in: Muscle & nerve, Vol. 39, Issue 6, pp. 739-53, (2009) (PubMed).
: "A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease." in: Genes & development, Vol. 21, Issue 19, pp. 2399-409, (2007) (PubMed).
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: "Loss of glycogen debranching enzyme AGL drives bladder tumor growth via induction of hyaluronic acid synthesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2015) (PubMed).
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- 抗原
- AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))
- 别名
- AGL (AGL 产品)
- 别名
- DDBDRAFT_0219237 antibody, DDBDRAFT_0234114 antibody, DDB_0219237 antibody, DDB_0234114 antibody, GDE antibody, 1110061O17Rik antibody, 9430004C13Rik antibody, 9630046L06Rik antibody, AI850929 antibody, C77197 antibody, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase antibody, glycogen debranching enzyme antibody, glycogen debranching protein antibody, amylo-1,6-glucosidase, 4-alpha-glucanotransferase antibody, AGL antibody, agl antibody, MMAH_RS03870 antibody, Agl antibody
- 背景
- AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.
- 分子量
- 174764
- 基因ID
- 178
- NCBI登录号
- NP_000019, NP_000633, NP_000634, NP_000635, NP_000636, NP_000637
- UniProt
- P35573
- 途径
- Cellular Glucan Metabolic Process
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