TSG101 抗体 (C-Term)
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北京 101111
Quick Overview for TSG101 抗体 (C-Term) (ABIN388927)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 340-370, C-Term
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预测反应
- M, Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This TSG101 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-370 amino acids from the C-terminal region of human TSG101.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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别名
- TSG101
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背景
- TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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分子量
- 43944
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基因ID
- 7251
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NCBI登录号
- NP_006283
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UniProt
- Q99816
抗原
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