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USP28 抗体 (N-Term)

USP28 适用: 人 WB 宿主: 兔 Polyclonal RB4435 unconjugated
产品编号 ABIN388921
发货至: 中国
  • 抗原 See all USP28 抗体
    USP28 (Ubiquitin Specific Peptidase 28 (USP28))
    抗原表位
    • 15
    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    AA 111-141, N-Term
    适用
    • 42
    • 17
    • 2
    • 1
    • 1
    宿主
    • 54
    • 2
    • 1
    克隆类型
    • 56
    • 1
    多克隆
    标记
    • 19
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP28 antibody is un-conjugated
    应用范围
    • 33
    • 21
    • 13
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This USP28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-141 amino acids from the N-terminal region of human USP28.
    克隆位点
    RB4435
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP28 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    USP28 (Ubiquitin Specific Peptidase 28 (USP28))
    别名
    USP28 (USP28 产品)
    别名
    im:7138195 antibody, USP28 antibody, 9830148O20Rik antibody, AU022237 antibody, mKIAA1515 antibody, ubiquitin specific peptidase 28 antibody, USP28 antibody, usp28 antibody, Usp28 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    122491
    基因ID
    57646
    NCBI登录号
    NP_065937
    UniProt
    Q96RU2
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