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USP13 抗体 (N-Term)

This anti-USP13 antibody is a 兔 多克隆 antibody detecting USP13 in WB. Suitable for 人.
产品编号 ABIN388900
发货至: 中国

Quick Overview for USP13 抗体 (N-Term) (ABIN388900)

抗原

See all USP13 抗体
USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

适用

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宿主

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克隆类型

  • 43
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多克隆

标记

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This USP13 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB4301
  • 抗原表位

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    AA 156-186, N-Term

    预测反应

    B

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This USP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human USP13.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

    别名

    USP13

    背景

    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

    分子量

    97327

    基因ID

    8975

    NCBI登录号

    NP_003931

    UniProt

    Q92995

    途径

    SARS-CoV-2 Protein Interactome
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