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USP7 抗体 (C-Term)

This anti-USP7 antibody is a 兔 多克隆 antibody detecting USP7 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN388889
发货至: 中国

Quick Overview for USP7 抗体 (C-Term) (ABIN388889)

抗原

See all USP7 抗体
USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

适用

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宿主

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克隆类型

  • 70
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多克隆

标记

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This USP7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4281
  • 抗原表位

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    AA 1060-1090, C-Term

    预测反应

    M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This USP7 (HAUSP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1060-1090 amino acids from the C-terminal region of human USP7 (HAUSP).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

    别名

    USP7 (HAUSP)

    背景

    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

    分子量

    128302

    基因ID

    7874

    NCBI登录号

    NP_003461

    UniProt

    Q93009
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